Peptide Chemistry• Intermediate
Peptide Stability and Degradation Pathways: Deamidation, Oxidation, and Hydrolysis
What are the primary chemical degradation pathways of research peptides in aqueous solution?
Research peptides are susceptible to several chemical degradation pathways when introduced to aqueous environments. This article explores the mechanisms of deamidation, oxidation, and hydrolysis, providing researchers with evidence-based strategies to maintain peptide stability in the laboratory.
Peptide Chemistry• Beginner
What Are Peptides?
What are peptides and how do they differ from proteins?
Peptides are short chains of amino acids linked by peptide bonds, typically containing 2–50 residues. They function as signaling molecules, research tools, and structural building blocks in biochemistry and pharmacology, distinct from proteins primarily by chain length.