Reconstituted Peptide Shelf Life: What the 28-Day Rule Really Means
How long do reconstituted peptides last, and what does the 28-day rule actually mean?
The 28-day rule is an official default beyond-use period for punctured, preserved multidose containers, it addresses sterility and container integrity, not peptide chemical stability. Actual peptide stability in solution depends on sequence, solvent, pH, concentration, preservatives, temperature, light/oxygen exposure, container adsorption, and freeze-thaw history.
By PepMarket Research Team
What Does Lyophilized Mean?
What does lyophilized mean and why are research peptides sold as lyophilized powder?
Lyophilization (freeze-drying) is a dehydration process that removes water from a product by freezing it and then subliming the ice under vacuum. For research peptides, lyophilization produces a stable dry powder with extended shelf life compared to aqueous solutions.
How Should Research Peptides Be Stored?
How should research peptides be stored, both lyophilized and reconstituted?
Lyophilized research peptides should be stored at -20°C or colder in a desiccated environment. Once reconstituted, peptide solutions should be aliquoted, kept at 4°C for short-term use, or frozen at -20°C/-80°C for long-term storage, avoiding repeated freeze-thaw cycles.