Cellular Research

IGF-1 LR3

Also known as: Long R3 IGF-1

IGF-1 LR3 is a long-acting analog of human insulin-like growth factor 1. It is engineered to have a reduced affinity for IGF-binding proteins, increasing its systemic half-life.

Molecular Properties

Molecular Formula

C400H625N111O115S9

Molecular Weight

9111 g/mol

CAS Number

946870-27-7

Research History

Created to provide a more potent tool for cell culture and metabolic research than native IGF-1, which is rapidly cleared by binding proteins.

Studied Mechanisms

Activates the IGF-1 receptor, promoting cell proliferation, protein synthesis, and muscle hypertrophy in experimental models.

Storage Reference

Store at -20°C for long-term; keep refrigerated after reconstitution.

Handling Reference

Avoid repeated freeze-thaw; keep stable in buffer.