NAD+
Also known as: Nicotinamide adenine dinucleotide, Coenzyme I
NAD+ is a critical coenzyme found in all living cells. It is essential for metabolism, serving as a key electron carrier in redox reactions and a substrate for enzymes like sirtuins and PARPs.
Molecular Properties
Molecular Formula
C21H27N7O14P2
Molecular Weight
663.43 g/mol
CAS Number
53-84-9
Research History
Discovered in 1906, NAD+ has become a cornerstone of metabolic and aging research. The decline of NAD+ levels with age has driven extensive study into its supplementation.
Studied Mechanisms
NAD+ acts as a coenzyme for sirtuins, regulating gene expression and DNA repair. It is crucial for ATP production and mitochondrial energy homeostasis.
Storage Reference
Store at -20°C, protected from light and moisture.
Handling Reference
Reconstitute with appropriate buffer; avoid repeated freeze-thaw cycles.