Endocrine Research

PT-141

Also known as: Bremelanotide

PT-141 is a synthetic peptide analog of alpha-MSH. It functions as a melanocortin receptor agonist and is studied for its effects on the central nervous system.

Molecular Properties

Molecular Formula

C50H68N14O10

Molecular Weight

1025.2

CAS Number

189691-06-3

Research History

Derived from the peptide Melanotan II, PT-141 was specifically modified to remove tanning properties while focusing on CNS activity through activation of the melanocortin receptors.

Studied Mechanisms

PT-141 crosses the blood-brain barrier to act as an agonist at the MC3R and MC4R receptors, modulating neurotransmitter pathways involved in sexual motivation and endocrine feedback.

Storage Reference

-20°C

Handling Reference

Standard aseptic peptide handling