SLU-PP-332
Also known as: SLU-PP-332 ERR agonist
SLU-PP-332 is a synthetic small-molecule agonist that targets Estrogen-Related Receptors (ERRs). It is designed to mimic the physiological effects of exercise by modulating metabolic gene expression.
Molecular Properties
Molecular Formula
C18H14F3N3O2S
Molecular Weight
393.38
CAS Number
2228795-31-0
Research History
SLU-PP-332 was developed as a tool to investigate the therapeutic potential of ERR activation. Recent studies have demonstrated its capacity to increase oxidative capacity in muscle tissue.
Studied Mechanisms
The compound acts as a selective agonist for ERR-alpha, beta, and gamma. By binding to these receptors, it upregulates genes involved in mitochondrial biogenesis and fatty acid oxidation, effectively 'exercising' cells in vitro.
Storage Reference
-20°C in dry conditions
Handling Reference
Soluble in DMSO; use standard chemical safety protocols